To ensure the quality of the clinical application of medical equipment and patient safety, the quality control results of 48 ventilators have been analyzed. The analysis result can bring more benefits to maintenance of ventilator in latter usage. The opinions on how to maintain ventilators in order to improve the intact ratio and utilization ratio are proposed though conduct the quality control and results analysis of the different brands ventilators from clinical departments in our hospital. Three proposals on improving the quality of clinical application have been offered by analyzing the incompetent factors which cause 11 ventilators fail to pass quality control test. The effective implementation of operational suggestions can provide guarantee for credible quality and safe running of medical equipment.