Domiciliary ventilation is associated with survival benefits in patients with neuromuscular disease and has also been used when chest wall and lung diseases result in respiratory insufficiency. Patients may receive support nocturnally or continuously, provided invasively by tracheostomy or non-invasively by facemask. The LTV series of ventilators was originally developed for domiciliary ventilation. Supplemental oxygen is usually not required in patients with neuromuscular disease and the ability of these ventilators to operate on battery without compressed gas supply maximizes portability, enabling them to be mounted on electrical wheelchairs.